The research team of Genetrump Co., Ltd., funded by the Science and Technology Development Fund (FDCT), has conducted industrial production and preclinical research on the topical formulation of Eucommia ulmoides polysaccharides (EUP) for the treatment of diabetic foot ulcers. The project primarily focuses on the extraction and the isolation of active polysaccharides from Eucommia ulmoides, which accelerate revascularization, promote cell adhesion and migration, as well as expedite wound healing.
The company was founded in 2018 by Prof. Wang Chunming and Dr. Zhang Zhe from the State Key Laboratory of Quality Research in Chinese Medicine at the University of Macau. Its main area of expertise lies in the field of natural polysaccharide active molecules. In 2021, the company established a subsidiary within the Guangdong-Macao In-Depth Cooperation Zone in Hengqin. The subsidiary is responsible for its research and market promotion in the sectors of healthcare and fast-moving consumer goods. In the same year, the company signed a contract with the Livelihood Affairs Bureau of Guangdong-Macao In-Depth Cooperation Zone in Hengqin, receiving funding as an outstanding Macao entrepreneurial project. They are actively driving the development of medication for diabetic foot ulcers. Based on this development, they have signed development contracts on formulation with the Zhuhai College of Science and Technology, and then entered into contract manufacturing agreements with pharmaceutical companies in Guangdong and Macao. These complete the construction of industrial production and quality standardization.
Genetrump is primarily built upon two core technology platforms: a world-leading platform for natural polysaccharide extraction and a platform for directed enzymatic hydrolysis and modification of polysaccharides. They have established a complete industry chain business system from raw materials to medical end products and functional skincare products, serving pharmaceutical, cosmetics, health supplement manufacturing companies, medical institutions and end users around the world. The company has developed related cosmetic raw material products, antiseptic and cosmetic products, which are already on the market with an accumulated revenue of approximately RMB 2 million.
As an enterprise which has introduced the advanced natural polysaccharide active molecule, Genetrump is both rooted in Macao and the Greater Bay Area. By utilizing active natural polysaccharide molecules in combination with the advanced formulation technology, they aim to break the international monopoly in polysaccharide extraction and functional modification with the objective of developing high-performance polysaccharide molecules that belong to China. Genetrump aspires to become a leading enterprise in the field of active polysaccharide molecules and polysaccharide medications.


