To optimize the use of mesenchymal stem cells (MSCs) derived from adult tissues for the treatment of diabetic foot ulcers, the cytokine secretion is adopted to stimulate endogenous cell regeneration, thereby promoting local cell proliferation and vascular regeneration. Xu Renhe, the Distinguished Professor and Associate Dean of the Faculty of Health Sciences (FHS) of the University of Macau (UM), pioneered the use of MSCs which are differentiated from human embryonic stem cells to achieve long-term artificial proliferation, effectively addressing the issue of mass production. With the support of the Science and Technology Development Fund (FDCT), the UM FHS collaborates with relevant institutions in the Greater Bay Area through cross-regional industry-university-research cooperation to promote the transformation of research achievements. The FHS conducts basic and animal research, while Zhuhai Hengqin ImStem Biotechnology Co., Ltd. produces clinical-grade stem cell ointments. Afterwards, clinical trials will be conducted at Zhuhai People’s Hospital.
 
    Through innovative collaboration between industry, university and research, this achievement is expected to generate a series of new technologies and products, cultivate new talents in the field of science and technology, as well as contribute to the development of the technology industry in Macao and the Greater Bay Area. This will result in significant economic and social benefits.